P1513 Myocardial work analysis is a potential novel tool to diagnose subclinical cardiac dysfunction in cirrhotic cardiomyopathy

Is Subclinical Thyroid Dysfunction Associated With with Coronary Heart Disease?

Introduction: Previous cohort studies reported contradictory data on the association between subclinical thyroid dysfunction and coronary heart disease (CHD). Regarding this, the present study was conducted to illuminate this relationship. Materials and Methods: For the purpose of the study, 3,066 participants employed in a study conducted by Azizi et al. aged ≥ 20 years were subjected to thyro...

Cardiac work and myocardial substrate extraction in congestive cardiomyopathy.

Myocardial dysfunction in hypertrophic cardiomyopathy.

Cardiomyopathy To The Editor: We note with interest Nagueh et al’s1 recent observation that the reduction of tissue Doppler (TD) velocities in mitral annulus excursion was highly sensitive and specific for the detection of individuals carrying hypertrophic cardiomyopathy (HCM)–causing mutations in HCM families, even in the prehypertrophic phase. Any clinical tool that can reliably identify subt...

Subclinical myocardial dysfunction in Rett syndrome.

AIMS Rett syndrome (RTT) is a rare neurodevelopmental disorder frequently linked to methyl-CpG-binding protein 2 (MeCP2) gene mutations. RTT is associated with a 300-fold increased risk of sudden cardiac death. Rhythm abnormalities and cardiac dysautonomia do not to fully account for cardiac mortality. Conversely, heart function in RTT has not been explored to date. Recent data indicate a previ...

Persisting myocardial sympathetic dysfunction in takotsubo cardiomyopathy

A 73-year-old woman without a cardiovascular history was admitted with chest discomfort, dizziness, and nausea after an emotional meeting with the staff of a nursing home. She experienced the same complaints some years before when her father died. On admission the patient was in cardiogenic shock. Auscultation of the heart revealed a grade 3/6 systolic murmur radiating to the left axilla. The e...